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Varicella zoster immunoglobulin VZIG shortage - March 2019

Varicella zoster Immunoglobulin (VZIG) is a scarce blood product that is offered to susceptible individuals at high risk of severe chickenpox following an exposure. This includes immunosuppressed individuals, young babies in their first week of life and pregnant women. There is currently a significant shortage of VZIG due to manufacturing issues. In response to the supply problems and based on advice issued by Public Health England (PHE) the use of VZIG in Scotland is restricted to susceptible women exposed in the first 20 weeks of pregnancy and neonates. Antiviral agents are recommended for post exposure prophylaxis for pregnant women exposed after 20 weeks and immunosuppressed individuals. See the detailed guide “Updated restrictions on use of VZIG during supply shortage: advice for health professionals”.  It is important that these are followed to ensure stock preservation 


Page updated March 2019