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CORONAVIRUS (COVID-19)

*UPDATED* Hospital visiting changes, home testing kits, Vaccine info, general info and guidance for public, NHSGGC staff, and community-based services.

Clinical Tests Available

Clinical Tests Available

Please see the departmental user manual or contact the department: 0141 354 9513 (89513)/0141 354 9514 (89514) for further information.

 

Name of Test

Specimen/Container Requirements:

Further Information:

Routine Histopathology including Immunohistochemistry and Molecular Analysis

Fix specimens as soon as possible (except where the testing requires fresh samples).

Fix the specimens with 10% Neutral Buffered formalin (ideally at least 10 times the volume of the specimen should be used, however this will not be practical for larger specimens, in this case aim for at least 3 times the volume of the specimen).

Package according to legislation with a minimum:

·leak proof container (specimen)

·sealable bag containing absorbent material

·secondary, opaque container (this can contain multiple specimens)

 

Fresh Samples – only send samples fresh if there is a clinical need, otherwise fix as per instructions. If in doubt, please discuss with the appropriate consultant pathologist.

 

Samples to be placed in a purple specimen bag.

Frozen Section

Intraoperative Samples (non-neurosurgical)

MOHS rapid interoperative diagnosis

 

DO NOT ADD ANY FIXATIVE! Send the sample FRESH and IMMEDIATELY!

Place in clearly labelled container

Indicate “For Frozen Section” on form and include details of who to contact with report.

Contact the laboratory (89513/89514)upon specimen dispatch

Do not send FRESH specimens with a known/suspected DANGER OF INFECTION (e.g. TB, HIV, COVID-19 etc.)

Contact lab (89513/89514)  in advance with details of the:

·Expected arrival/delivery time

·Patients name/identifier

·Name and contact details of the caller

·Page / contact details for communicating the results (confirm if the same as the caller)

 

Samples to be placed in a purple specimen bag.

Immunofluorescence

Skin, Renal and Conjunctival Biopsies

 

Venous Blood

DO NOT FIX THE SAMPLE IN FORMALIN!

Send skin, renal or conjunctival biopsies in Michel’s fixative

Venous blood that requires immunofluorescence should arrive in a Vacuette® blood collection tube.

Place in clearly labelled container

Specimens that are suspected or are known DANGER OF INFECTION with category 2 organisms (e.g. HIV, Hep B, Hep C) are accepted for testing.

 

Do not send FRESH specimens with a known/suspected DANGER OF INFECTION from Category 3/4 organisms (e.g. TB, HIV, CJD, etc.)

A negative COVID-19 sample from the patient within 72 hours before the sample was taken is required for the specimen to be accepted for immunofluorescence.

Michel’s Fixative must be stored between 2-250c prior to use.

Michel’s Fixative is capable for preserving the specimen for up to 5 days without any deterioration.

Michel’s Fixative is available upon request from:

Pathology Department, Level 3, Laboratory Medicine and Facilities Management Building, Queen Elizabeth University Hospital, 1345 Govan Rd, Glasgow, G51 4TF (0141 354 9518/9518).

Samples to be placed in a purple specimen bag.

 

Neurosurgical Intraoperative Samples (Brain smear or frozen section)

DO NOT ADD ANY FIXATIVE! Send the sample FRESH and IMMEDIATELY!

Place in clearly labelled container

Contact the laboratory (89530 or page 17627) upon specimen dispatch

 

Contact lab (89530 or page 17627)  at least 24 hours in advance with details of the:

·Surgical Procedure

·Location

·Expected arrival/delivery time

·Patients name/identifier

·Name and contact details of the caller

·Page / contact details for communicating the results (confirm if the same as the caller)

 

Samples to be placed in a purple specimen bag.

 

Neurosurgical biopsy for Paraffin Histology

The sample should be fixed with 10% formal saline

DO NOT FIX WITH 10% NEUTRAL BUFFERED FORMALIN!

Contact the laboratory (89530 or page 17627) upon delivery

10% formal saline will be supplied by the Neuropathology section of the lab when requested by theatre.

 

Samples to be placed in a purple specimen bag

Amputation

The orthopaedic theatre should contact Pathology specimen reception (89513/89514) at least 24 hours before procedure is scheduled so that a suitable specimen container can be supplied

Large amputations that have a high ratio of surface area covered by skin should be sent fresh and not fixed

To contain potential leakage amputations should be placed into a large plastic bag or wrapped in drapes before being put into the specimen container.

NEVER use yellow or orange bags/containers as this corresponds to the code for waste incineration

Products Of Conception

Please ensure the specimen arrives with a FULLY COMPLETED specimen request form and the CORRECT & FULLY COMPLETED consent form (SDT/SD8/FORM 2)

SD7 Form [PATH-MOR-LF-003]: Authorisation for sensitive disposal following pregnancy loss

SD8 Form [PATH-MOR-LF-004]: Release of Tissue/Family wants to take pregnancy loss away from hospital

Pregnancy Loss FORM 2: Authorisation for burial or cremation following pregnancy loss up to 23 weeks and 6 days gestation.

Placenta

The Placental Request Form MUST be used (Order Code MIS260726 for NHSGGC Users, If not a NHSGGC user please contact the laboratory and we will email over a PDF (0141 354 (8)9531)

Please see the full Placenta Histology Requests section for more information on the clinical information required and how these specimens are triaged within the department.

The form MUST include the following information:

·Mother’s name

·Mother’s date of birth

·Address

·Hospital number and CHI number

·Date of delivery

·Date placenta sent for pathology examination

·Referring Hospital

·Referring Consultant

·Midwife or trainee doctor’s name and contact extension/bleep number

·Gravida and parity

·GESTATION

·Apgars of the baby/babies delivered

·Weight of the baby/babies delivered

 

Samples to be placed in a purple specimen bag.

Urgent Paediatric Specimens

 

Frozen Sections

 

Fresh tumour Biopsies

 

Fresh Tumour Resections

Any queries regarding urgent specimens should be addressed by telephoning the paediatric office on 89478 and asking to speak to the duty paediatric pathologist. Any out-of-hours queries should be directed to the on-call pathologist who can be contacted via hospital switchboard. The paediatric laboratory team may be contacted on 89531.

All cases must be booked in advance (ideally the day before) by telephoning 89478 and discussing the case with the duty paediatric pathologist.

The paediatric laboratory team may be contacted on 89531.

Package according to legislation with a minimum:

·leak proof container (specimen)

·sealable bag containing absorbent material

·secondary, opaque container (this can contain multiple specimens)

 

All fresh paediatric specimens must be conveyed immediately in person or by porter to pathology (3rd floor, Laboratory Medicine Building). The surgical team is responsible to arrange this.

Samples to be placed in a purple specimen bag.

 

Routine Paediatric Specimens

Fix as per routine histopathology specimens above, unless the specimen is indicative of paediatric neoplasia/cancer/tumour. In this case telephone the paediatric office on 89478 and asking to speak to the duty paediatric pathologist.

Paediatric rectal biopsies for diagnosis of Hirschsprung’s disease may be sent in formalin

Paediatric tonsils do not need to be sent fresh unless there is a high clinical suspicion of malignancy. These specimens may be sent in formalin.

 

The paediatric laboratory team may be contacted on 89531.

Package according to legislation with a minimum:

·leak proof container (specimen)

·sealable bag containing absorbent material

·secondary, opaque container (this can contain multiple specimens)

 

All fresh paediatric specimens must be conveyed immediately in person or by porter to pathology (3rd floor, Laboratory Medicine Building). The surgical team is responsible to arrange this.

Samples to be placed in a purple specimen bag.

 

Paediatric Renal Biopsies

Contact lab (89531) with AS MUCH NOTICE AS POSSIBLE before taking a biopsy, the case may need to be discussed with the duty pathologist before proceeding.

The deadline for same day processing is 13:00

 

NATIVE & TRANSPLANT BIOPSIES: These specimens will normally be collected in theatre by a biomedical scientist who will separate the sample for immunofluorescence and electron microscopy.

 

Adult Renal Biopsies (Medical/Native/Transplant)

If URGENT the specimen should be sent directly to the laboratory by porter/eagle couriers.

 

The deadline for same day processing is 13:00

 

Each patient sample should be received in 3 parts: Main (largest) sample in formalin, a sample in buffer for immunofluorescence and a sample in 2% Glutaraldehyde for electron microscopy.

 

The clinical information MUST specify if the renal biopsy is Transplant, Native (Medical) or other

 

 

THE SPECIMEN MUST BE HANDED TO A MEMBER OF LABORATORY STAFF ON DELIVERY

 

Freshly prepared glutaraldehyde has a 7 day shelf life and must be stored to 4-80c prior to use.

Buffer and Glutaraldehyde are available with advance notice from:

Pathology Department, Level 3, Laboratory Medicine and Facilities Management Building, Queen Elizabeth University Hospital, 1345 Govan Rd, Glasgow, G51 4TF (0141 354 9513/9514).

All unused Glutaraldehyde should be returned to the EM unit for disposal.

 

Samples to be placed in a purple specimen bag.

Adult Renal Biopsies (Tumour/Cancer/RCC)

Fix specimens in formalin as soon as possible

 

The clinical information must specify that the renal biopsy is querying Tumour/Cancer/RCC.

 

Samples to be placed in a purple specimen bag.

Cardiac Transplant Biopsies (Adult)

If URGENT the specimen should be sent directly to the laboratory by taxi/courier.

 

The deadline for same day processing is 13:00

 

Contact the laboratory reception (89513/89514) to inform them of the biopsy and indicate whether this is a routine or urgent biopsy. This information will be passed to the duty cardiac pathologist.

Alternatively, contact the duty cardiac pathologist directly to discuss the case.

THE SPECIMEN MUST BE HANDED TO A MEMBER OF LABORATORY STAFF ON DELIVERY

 

Samples to be placed in a purple specimen bag.

 

Native Cardiac (Endomyocardial) Biopsies

If URGENT the specimen should be sent directly to the laboratory by taxi/courier.

 

The deadline for same day processing is 13:00

 

Contact the laboratory reception (89513/89514) to inform them of the biopsy and indicate whether this is a routine or urgent biopsy. This information will be passed to the duty cardiac pathologist.

Alternatively, contact the duty cardiac pathologist directly to discuss the case.

If a storage/metabolic disorder is being considered, then contact the duty cardiac pathologist to discuss the need for sampling for electron microscopy.

IF URGENT, THE SPECIMEN MUST BE HANDED TO A MEMBER OF LABORATORY STAFF ON DELIVERY

 

Samples to be placed in a purple specimen bag.

 

Muscle Biopsy

Contact lab (89530 or page 17627) with AS MUCH NOTICE AS POSSIBLE before receipt of the biopsy.

An additional muscle biopsy request (linked) form MUST be used, please follow the instructions on this form.

 

The laboratory can receive muscle biopsies between 09:00 and 16:00, Monday – Friday (excluding public holidays).

 

Specimens must be placed in a dry, clean universal container. No saline, gauze or formalin should be used.

 

If the sample will take longer than 20 minutes to reach the department it is recommended that the universal container (NOT the muscle directly) is put into a bag of ice.

Contact lab (89530 or page 17627, for external sites: 0141 354 9530)  with AS MUCH NOTICE AS POSSIBLE providing details of the:

·Any Danger/Risk of Infection

·Expected arrival/delivery time

·Patients name/identifiers

·Name and contact details of the caller

·Page/contact details for communicating the results (confirm if the same as the caller)

 

THE SPECIMEN MUST BE HANDED TO A MEMBER OF LABORATORY STAFF ON DELIVERY

 

Samples to be placed in a purple specimen bag.

Nerve Biopsy – for Frozen Section

DO NOT ADD ANY FIXATIVE! Send the sample FRESH and IMMEDIATELY!

Place in clearly labelled container

Contact the laboratory (89530 or page 17627, for external sites: 0141354 9530) upon specimen dispatch

 

Contact lab (89530 or page 17627)  at least 24 hours in advance with details of the:

·Surgical Procedure

·Location

·Expected arrival/delivery time

·Patients name/identifier

·Name and contact details of the caller

·Page / contact details for communicating the results (confirm if the same as the caller)

 

Samples to be placed in a purple specimen bag.

 

 

Last Updated: 30 April 2021