The pathology department offers a service for immunofluorescence testing on skin, renal, conjunctival and oral biopsies as well as venous blood.
Venous blood that requires immunofluorescence should be sent to the department in a Vacuette® blood collection tube. Skin, Renal, Oral and Conjunctival Biopsies requiring immunofluorescence should be placed in Michel’s fixative immediately after collection.
Michel’s fixative is capable of preserving fresh tissue for up to 5 days before there is any deterioration in the sample. The request form is checked for the date a sample is taken, to ensure that it has been received within time. Michel’s fixative is available from the pathology department upon request. The fixative should be stored between 2-250c and not be used after it has reached its expiry date.
Any sample currently taken for immunofluorescence testing is required to have had a negative COVID-19 test within 72 hours prior to the sample being taken. This is checked and confirmed using clinical portal. Any immunofluorescence samples received without a negative COVID-19 test will NOT be tested.
Specimens that are suspected or are known to contain blood borne viruses (e.g. HIV, Hep B, and Hep C) are classified as Category 2 and can be dealt with using the appropriate safety precautions.
Specimens suspected or known to have Category 3 organisms (e.g. TB, Leprosy, and Anthrax) or Category 4 organisms (e.g. Ebola, Lassa Fever and Haemorrhagic Fever) or CJD are not suitable for analysis via immunofluorescence.
For further information regarding immunofluorescence or danger of infection samples, please contact the Immunocytochemistry Department of the pathology laboratory (0141 354 9518/89518).