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COVID-19 (Coronavirus info)

Information and guidance for public, NHSGGC staff, and community-based services.  Hospital visiting restrictions now in place.

Uncertainty of measurement

How reliable is my patient's result?


Measurement of uncertainty refers to the extent of variation of results at a given value within our assays. This can be affected by a multitude of factors. We generate data over an extended period of time for each of our quantitative assays in order to provide a measure of the expected range in results.

This aids the clinician to determine the significance of any change in concentration of a given analyte - particularly relevant for those tests used in monitoring.


Summary tables below contain uncertainty of measurement values for our assays.

  • Automated serology - includes total IgE, allergen specific IgE, IgA & IgG TTG (coeliac serology), CCP antibodies, MPO/PR3 antibodies, GBM antibodies, dsDNA antibodies, ENA antibodies (screen & identities), IgG Aspergillus antibodies, tryptase.
  • Neuroimmunology - includes acetylcholine receptor antibodies, MAG antibodies, GAD antibodies (Stiff Person Syndrome).
  • Immunochemistry - includes functional antibodies, intrinsic factor, GAD antibodies (diabetic serology), serum free light chains, C1 inhibitor (quantitation).
  • Complement function - includes C1 inhibitor function, classical complement function, alternative complement function.
  • Flow cytometry - including lymphocyte subsets analysis for CD3+ CD4+/CD8+ T cells, CD19+ B cells and CD16/56+ NK cells (percentages and absolute counts)


Please contact the laboratory to discuss if required.

Last Updated: 21 October 2021