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Information and guidance for public, NHSGGC staff, and community-based services.  Hospital visiting restrictions now in place.

Prostate Specific Antigen (PSA)

Prostate specific antigen (PSA), a protease, is a normal constituent of seminal fluid. It is produced by the secretory cells of the acini and ducts of the prostate and other cells expressing the nuclear androgen receptor.
PSA is measured to aid the diagnosis and for monitoring of prostate cancer.
PSA may be spuriously elevated in a number of situations: catheterisation; acute retention of urine; urinary infection; ejaculation or vigorous exercise; DRE; prostate biopsy. Where these may have contributed to an elevated PSA result, suggest repeat in 6 weeks.
Sample Requirements and Reference Ranges
Sample type  Serum
Container  SST
Precautions  None
Minimum volume  2 mL
Reference range  Age (yrs)          PSA (μg/L)

 <60                      ≤ 3.0

 60 - 69                 ≤ 4.0

 ≥70                      ≤ 5.0

Turnaround time  1 day
Method  Abbott Architect
Quality Assurance
Last Updated: 10 July 2020