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Urine Steroid Profile

A urine steroid profile includes all major metabolites of steroids, including glucocorticoids, mineralocorticoids and precursors.

The test is used to identify genetic disorders of steroid metabolism, though the screening or diagnostic test for congenital adrenal hyperplasia should be serum 17-hydroxyprogesterone. Steroid profiling is also useful to detect abnormal steroid secretion from adrenal and gonadal tumours.

Sample Requirements and Reference Ranges

Sample type  Urine (Aliquot of 24 hour urine for adults; random for children)
Container  Plain urine container (no preservative)
Precautions  None
Minimum volume

 10 mL preferred.

 Smaller volume acceptable for babies (min. 2 mL)

Reference range  Age and sex dependent. Interpretation accompanies each report.
Turnaround time  28 days
Method  Gas chromatography - mass spectrometry
 
Quality Assurance
SKML/UCLH