A urine steroid profile includes all major metabolites of steroids, including glucocorticoids, mineralocorticoids and precursors.
The test is used to identify genetic disorders of steroid metabolism, though the screening or diagnostic test for congenital adrenal hyperplasia should be serum 17-hydroxyprogesterone. Steroid profiling is also useful to detect abnormal steroid secretion from adrenal and gonadal tumours.
Sample Requirements and Reference Ranges
|Sample type||Urine (Aliquot of 24 hour urine for adults; random for children)|
|Container||Plain urine container (no preservative)|
10 mL preferred.
Smaller volume acceptable for babies (min. 2 mL)
|Reference range||Age and sex dependent. Interpretation accompanies each report.|
|Turnaround time||28 days|
|Method||Gas chromatography - mass spectrometry|