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COVID-19 (Coronavirus info)

Information and guidance for public, NHSGGC staff, and community-based services.  Hospital visiting restrictions now in place.

Sex Hormone Binding Globulin (SHBG)

Sex hormone binding globulin (SHBG) is a large 80-100 kDa glycoprotein that functions to transport sex hormones around the body. It has a high affinity for 17β-hydroxy steroids such as testosterone and oestradiol. Concentrations of SHBG are influenced by many factors. SHBG will be increased by elevated concentrations of circulating oestrogens (including the oral contraceptive pill), hyperthyroidism, liver disease and excess alcohol. SHBG will be decreased by increasing body mass index, polycystic ovarian syndrome and hypothyroidism.

Sample Requirements and Reference Ranges

Sample type  Serum
Container  SST
Precautions  None
Minimum volume  2 mL
Reference range  Age                       Male (nmol/L)      Female (nmol/L)

 3 - 10 years              45 - 220              50 - 170

 10 - 12 years            22 - 188              38 - 129

 Adult                         13 - 70                20 - 155

Turnaround time  1 day
Method  Abbott Architect
Quality Assurance
Last Updated: 30 April 2019