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Covid-19 (Coronavirus)

Information and guidance for public, NHSGGC staff, and community-based services.  Hospital visiting restrictions now in place.

Insulin - like Growth Factor 1 (IGF-1)

Insulin-like growth factor 1 (IGF-1) is a peptide hormone, very similar to insulin. It is a major growth factor, which is synthesised by most cells and tissues. Circulating IGF-1 is produced by the liver in response to growth hormone (GH). IGF-1 concentration is increased in acromegaly, decreased in growth hormone deficiency and altered in systemic illness and malnutrition.

It is often measured along with growth hormone in the investigation of disorders of GH secretion. It is also used to monitor patients with acromegaly and those on growth hormone therapy.

Sample Requirements and Reference Ranges

Sample type  Serum
Container  SST
Precautions  None
Minimum volume  2 mL
Reference range  Age (yr)      Males (μg/L)     Females (μg/L)

    <2              15 - 157            17 - 151

    2 - 4           28 - 247            25 - 198

    5 - 7           46 - 349            39 - 272

   8 - 10          67 - 442            59 - 371

  11 - 13         89 - 503            82 - 465

  14 - 16         104 - 510          97 - 502

  17 - 25         105 - 410          96 - 417

  26 - 39         81 - 249            72 - 259

  40 - 54         63 - 201            57 - 197

  55 - 65         49 - 191            43 - 170

  65+              39 - 186            35 - 168

Turnaround time  7 days
Method  IDS iSYS
 
Quality Assurance
UK NEQAS
Last Updated: 30 April 2019