Overview

People with Osteogenesis Imperfecta have weak bones, which makes them susceptible to fractures.

Introduction

People with Osteogenesis Imperfecta (OI) have weak bones, which makes them susceptible to fractures.

Osteogenesis Imperfecta or brittle bone disease is a genetic condition that causes abnormality in collagen protein that the body needs for bones as well as other structures such as skin, ligaments and teeth. Seven forms of OI have been described. They include mild, moderate and severe forms.