Medicines for Huntington's disease, which can be taken in liquid form in many cases if needed, are described below.
Most of these medications have side effects, such as extreme tiredness. However, it may sometimes be difficult to tell whether these are symptoms of the condition or a result of the medication.
Antidepressants can help improve mood swings and treat depression. They include:
Side effects of antidepressants may include:
Mood stabilisers, particularly carbamazepine, may be considered as a treatment for irritability. Olanzapine can also help, along with sodium valproate and lamotrigine.
The dose of carbamazepine needs to be slowly increased and any side effects monitored. Carbamazepine can't be used during pregnancy.
The medications listed below suppress the involuntary movements – or chorea – seen in Huntington's disease. In the UK, antipsychotic medicines are usually preferred.
Antipsychotic medication may also help control delusions and violent outbursts. However, they may have severe side effects, such as:
Due to the possibility of experiencing these side effects, the lowest possible dose of antipsychotics are normally prescribed in the first instance.