Ehlers-Danlos syndromes (EDS) are a group of rare inherited conditions that affect connective tissue.
Connective tissues provide support in skin, tendons, ligaments, blood vessels, internal organs and bones.
There are several types of EDS that may share some symptoms, including:
The different types of EDS are caused by faults in certain genes that make connective tissue weaker. Depending on the type of EDS, the faulty gene may have been inherited from one parent, or both parents.
Sometimes the faulty gene isn't inherited, but occurs in the person for the first time.
EDS can affect people in different ways. For some, the condition is relatively mild, while for others their symptoms can be disabling. Some of the rare severe types can be life-threatening.
Hypermobile EDS is the most common type of EDS. Rarer types include classical EDS, vascular EDS and kyphoscoliotic EDS.