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Prenatal Screening


West of Scotland Prenatal Screening Service for  Down's syndrome.

This service is provided for 60% of the Scottish pregnant population in seven Health Boards in the West of Scotland:  Ayrshire and Arran, Dumfries and Galloway, Forth valley, Greater Glasgow and Clyde, Lanarkshire, Highland and the Western Isles. In the West of Scotland, over 22,000 women choose to have the prenatal screening test for Down's syndrome each year . This experience now makes the service one of the largest prenatal screening programmes in the UK.
Marked reductions in the birth incidences of neural tube defects and Down's syndrome  can be attributed to this programme and further improvements in sensitivity and specificity are being seen with the increasing use of new first trimester testing protocols for chromosome abnormalities. These use a combination of  Nuchal Translucency (ultrasound) and Biochemical testing.

With the recent  inclusion of  the NHS Greater Glasgow and Clyde area ,  routine 1st Trimester Combined Ultrasound and Biochemical screening is now available to all  pregnant women in the West of Scotland.
The Biochemical Genetics division has been particularly active in research and development in Down's syndrome screening over the last decade (over 50 publications) and this work is continuing through externally funded research projects and national and international collaborations. All enquiries to : 0141 354 9274  

Information for Users

Information and Guidelines for Health Professionals

National Services Division (NSD)  - Information on Pregnancy Screening Programmes

National Services Division (NSD)  - Pregnancy Screening Developments ( Protocols)